Navigation on this site is not optimized for your browser

Please use a recent version of Google Chrome, Mozilla Firefox, Safari or Microsoft Edge to get the most out of the experience.

Find a modern browser

Amorphical ISS research results in new publication

Results obtained by AMORPHICAL from their microgravity research have been published. Their study, conducted during the Ax-1 mission on the ISS, made steps towards potential solutions to combat muscle atrophy and skeletal deterioration in astronauts, a crucial topic in any human space exploration effort.

The publication of their findings on “Amorphous Calcium Carbonate enhances osteogenic differentiation and myotube formation of human bone marrow derived mesenchymal stem cells and primary skeletal muscle cells under microgravity conditions” can be accessed here.

Astronauts face significant physiological challenges in space, including microgravity and increased radiation exposure, leading to muscle atrophy and skeletal deterioration. Amorphous Calcium Carbonate (ACC) shows promise in mitigating these effects by addressing bone-muscle crosstalk. Two studies conducted aboard the International Space Station investigated ACC’s effects on cell differentiation. The results demonstrate that ACC enhances differentiation of skeletal muscle cells into myotubes and bone marrow-derived stem cells into osteocytes, highlighting its potential for preventing muscle and bone deterioration in space conditions.

This research holds paramount significance, not only for advancing space exploration endeavors and facilitating future colonization plans but also for improving and prolonging human life on Earth.

The space experiment of Amorphical utilized SpacePharma‘s SPIC minilab, an automated device for cell culture. In short, cells are cultured in a microfluidic chip, in which the medium is periodically and automatically refreshed, and the temperature is controlled and maintained. Additionally, the system is equipped with microscopic imaging capability in real time. The SPIC minilab was accommodated in the ICE Cubes Facility of ESA’s Columbus module, receiving power and real-time data transfer to ground, during the Ax-1 mission, the first private mission to the ISS (launched April 8, 2022, and returned to Earth April 25, 2022).

For more information, explore the references below.

1st private mission to ISS
This website uses cookies
We use cookies and similar technologies to adjust your preferences, analyse traffic and measure the effectiveness of campaigns. You consent to the use of our cookies by continuing to browse this website.
  • Essentials Essentials


    Cookie that remembers the user's choice of cookie preferences


    The server saves the language chosen by the user to display the correct version of the pages

    Google Tag Manager

    Cookie set by Google Tag Manager. Google Tag Manager enables to manage website tags without editing code. All tags handled via Google Tag Manager are conditioned to the acceptance of the relevant cookie category.

  • Performance


    Cookie from Google Analytics allows us to anonymously count visits, the sources of these visits as well as the actions taken on the site by visitors.

This website uses cookies

We use cookies and similar techonologies to adjust your preferences, analyze traffic and measure the effectiveness of campaigns. You consent to the use of our cookies by continuing to browse this website.